Fine-needle aspiration cytology diagnosis of metastatic gastrointestinal stromal tumor in the liver: a report of three cases.

摘要: Gastrointestinal stromal tumor (GIST) is the designation for a major subset of gastrointestinal mesenchymal tumors that histologically, immunocytochemically, and genetically differ from leiomyomas, leiomyosarcomas, schwannomas. GISTs derive interstitial cells Cajal and, in addition to variable expression smooth muscle neural markers, they characteristically express CD34 CD117. The cytological appearance, including immunocytochemical mutational analysis c-kit gene primary GIST has been well described. To our knowledge, only two cases metastatic diagnosed by fine-needle aspiration (FNA) have reported. We illustrate three liver. Two had no prior history third case 4-yr previous duodenal tumor. Consistent immunocytochemistry ultrastructual studies supported diagnosis GIST. emphasize appropriate clinical radiological setting, confident can be established FNA lesions. Diagn. Cytopathol. 2002;27:298–302. © 2002 Wiley-Liss, Inc.