Polymeric nutrition as the primary therapy in children with small bowel Crohn's disease.
作者： R. M. BEATTIE , E. J. SCHIFFRIN , A DONNET-HUGHES , A. C. HUGGETT , P. DOMIZIO
DOI: 10.1111/J.1365-2036.1994.TB00338.X
关键词: Complete protein 、 Crohn's disease 、 Enteral administration 、 Gastroenterology 、 Ileum 、 Weight gain 、 Medicine 、 Internal medicine 、 Parenteral nutrition 、 Disease 、 C-reactive protein
摘要: SUMMARY Background: Recent studies in adults have shown that polymeric (whole protein) diets are as effective semi-elemental and elemental formulae for the induction of remission small bowel Crohn's disease. Whole protein more palatable cheaper. There been no confirming efficacy children. Patients Methods: We report our experience with seven children active disease given a casein-based, feed rich TGF-SbT2 (Specific Polymeric Diet; Nestl–Clintec; Vevey, Switzerland) complete nutrition 8 weeks. Results: Initial follow-up assessments were performed. All showed significant improvement activity, C-reactive returning to normal, an increase serum albumin good weight gain. ileal biopsies assessed reduced mucosal inflammation six children, healing two. Conclusion: In uncontrolled descriptive study we diet is therapeutic option children. By comprehensive demonstrated clinical biochemical remission, improved endoscopic appearance reduction terminal ileum.
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