作者: C C Poulton , L V Simon , B J Rice , S P Rider
DOI:
关键词: Air embolism 、 Oxygenator 、 Arterial line 、 Air entrainment 、 Cardiopulmonary bypass 、 Microbubbles 、 Biomedical engineering 、 Centrifugal pump 、 Stopcock 、 Materials science 、 Anesthesia
摘要: The objective of this study was to examine the interaction cardiopulmonary bypass venous air with assisted drainage, focusing on its production gaseous microemboli in arterial line. An in-vitro recirculating circuit containing fresh whole bovine blood monitored a pulsed-doppler microbubble detector. Air specific amounts injected into line and counts were obtained distal filter. Data recorded for unassisted vacuum-assisted centrifugal pump-assisted drainage. Centrifugal drainage produced over 300 microbubbles one minute filter when introduced circuit. Of these, 220 greater than 80 microns size. Vacuum-assisted no same amount However, did produce some stopcock left open 30 seconds. Unassisted at all levels entrainment. becomes entrained from variety sources. In typical gravity-drained situation, remains is dissipated reservoir by buoyancy filtration. an assisted-drainage subjected additional forces. degree negative pressure and, pump kinetic energy imparted cones or vanes pump. appears break small bubbles which become suspended blood, passing through reservoir, oxygenator, clinical setting, these would be passed patient's system.