Functional Hemispheric (A)symmetries in the Aged Brain-Relevance for Working Memory.

作者: Madalena Esteves , Ricardo Magalhães , Paulo Marques , Teresa C. Castanho , Carlos Portugal-Nunes

DOI: 10.3389/FNAGI.2018.00058

关键词: Superior parietal lobuleBrain activity and meditationLateralization of brain functionWorking memoryAngular gyrusPrecentral gyrusAudiologyPsychologyn-backLaterality

摘要: Functional hemispheric asymmetries have been described in different cognitive processes, such as decision-making and motivation. Variations the pattern of left/right activity associated with normal brain functioning, neuropsychiatric diseases. Such evolve throughout life are thought to decrease aging, but clear associations function never established. Herein, we assessed functional laterality during a working memory task (N-Back) healthy aging cohort (over 50 years old) these performance test. Activity lobule VI cerebellar hemisphere angular gyrus was found be lateralized right hemisphere, while precentral presented left > activation this task. Interestingly, 1-Back accuracy positively correlated superior parietal activation, which mostly due influence hemisphere. In conclusion, although regions were symmetrically activated N-Back task, aged individuals seems benefit from involvement lobule.

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