Activation of the PI3K/AKT pathway mediates FSH-stimulated VEGF expression in ovarian serous cystadenocarcinoma.

作者: Yan Huang , Keqin Hua , Xianrong Zhou , Hongyan Jin , Xiaojun Chen

DOI: 10.1038/CR.2008.70

关键词: Protein kinase BLY294002BiologyInternal medicineCystadenocarcinomaSurvivinAkt/PKB signaling pathwayVascular endothelial growth factorOvarian cancerCancer researchPI3K/AKT/mTOR pathwayEndocrinology

摘要: … and reduced exposure to FSH and LH 19, 20 . The FSH receptor (FSHR) and LH receptor (LHR) … Moreover, levels of ovarian and peritoneal FSH and LH seem to be elevated in ovarian …

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