In Vivo Analysis of the Anatomical Relationship of Coronary Sinus to Mitral Annulus and Left Circumflex Coronary Artery Using Cardiac Multidetector Computed Tomography: Implications for Percutaneous Coronary Sinus Mitral Annuloplasty

摘要: Objectives We sought to determine the in vivo anatomical relationships between mitral annulus (MA) and coronary sinus (CS) as well CS left circumflex artery using cardiac computed tomography. Background Percutaneous treatment of regurgitation (MR) by annuloplasty via is under development. Success such depends on close proximity MA CS. The data regarding this relationship humans are scant. investigated contrast multidetector Methods studied 25 normal individuals 11 patients with severe MR (3 4+) due valve prolapse. Separation was measured standard planes, 4-chamber (4C), 2-chamber (2C), 3-chamber views. Distance from ostium intersection (LCX), relation LCX were determined 3-dimensional mapping (Philips Brilliance, Philips Medical Systems, Amsterdam, Netherlands). Results There significant variance separation at all planes. increased lateral location (4C) decreased posterior (2C) group increase size. Left crossed 80% patients. a variable distance (86.5 ± 21 mm, range 37 123 mm) Conclusions variability humans. Coronary increases annular dilation, mainly posterolateral location. crosses majority times, but where it These features should be taken into consideration while selecting percutaneous strategies for repair.