The effect of antilymphocytic antibody on the humoral immune response of different strains of mice. V. Effects on the class and subclass of antibody produced, and the antibody responses of congenitally athymic mice

作者: K. James , G. W. Warr

DOI:

关键词: ImmunologyBALB/cGlobulinMolecular biologySubclassAntibody responseMode of actionAntibodyAntigenBiologyImmune system

摘要: Antilymphocytic globulin (ALG) depressed the antibody responses of mice to SRBC as measured in terms splenic PFCs IgM, IgG1, IgG2a and IgG2b specificity. This effect was apparent over a range antigen doses. ALG also reduced congenitally athymic SIII. The possible mode action is discussed light these, other, observations.

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