Immobilization of enzymes and antibodies to radiation grafted polymers for therapeutic and diagnostic applications

作者: Liang C. Dong , Gottfried Schmer , Allan S. Hoffman , Wayne R. Gombotz , Satoshi Uenoyama

DOI: 10.1016/1359-0197(86)90106-2

关键词: ChemistryPeroxidePolyethyleneMethacrylic acidImmobilized enzymeCopolymerSelf-healing hydrogelsPolymerPolymer chemistryGrafting

摘要: Abstract Pre-irradiation and mutual radiation grafting were employed to produce poly(methacrylic acid) (MAAc) hydrogels on polypropylene/polyethylene (PP/PE) copolymer films, PP films porous fibers of a plasma filter. A diphenyl picryl hydrazyl (DPPH) assay was developed measure the surface peroxide concentration pre-irradiated PP/PE prior grafting. Mutually grafted used for subsequent immobilization L-asparaginase while mutually immobilize schistosoma monoclonal antibody.

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