Burn Patients Infected With Metallo-Beta-Lactamase-Producing Pseudomonas aeruginosa : Multidrug-Resistant Strains

摘要: Background: Metallo-beta-lactamase (MBL) producing Pseudomonas aeruginosa in the burn patients is a leading cause of morbidity and mortality remains serious health concern among clinicians. Objectives: The aim this study was to detect MBL-producing P. determine multidrug-resistant (MDR) strains, respective resistance patterns. Patients Methods: In cross-sectional study, 270 strains were isolated from referred Ghotbeddin Burn Hospital, Shiraz, Iran. Among them, 55 hospitalized unit. Minimum inhibitory concentrations (MICs) MBLs determined by E-test method. Results: Of cases, 29 (53%) females 26 (47%) males. Injured patients’ ages ranged 16 87 years, with maximum number cases age group 36 years (n, 40; 72.7%). Overall, 32 accidental (60%), 22 suicidal burns (40%). patients, 17 expired (30%). All deaths due chemical exposures. antibiotic susceptibility testing method, ceftazidime most effective one 35 isolates (63.5%) resistant all 11 tested antibiotics. Conclusions: Routine microbiological surveillance careful vitro antibiotics prior prescription strict adherence hospital policy may help prevent, treat, control MDR pandrug -resistant (PDR) units.