High-frequency jet ventilation shortened the duration of gas embolization during laparoscopic liver resection in a porcine model

作者: D. Fors , K. Eiriksson , A. Waage , D. Arvidsson , S. Rubertsson

DOI: 10.1093/BJA/AEU087

关键词: MedicineVentilation (architecture)EmbolizationMechanical ventilationPositive pressureAir embolismHemodynamicsBlood flowEmbolismAnesthesia

摘要: Background Positive pressure mechanical ventilation causes rhythmic changes in thoracic and central blood flow. If entrainment occurs, it could be easier for carbon dioxide to enter through a wounded vein during laparoscopic liver lobe resection (LLR). High-frequency jet (HFJV) is ventilating method that does not cause pronounced or flow changes. This study aimed investigate whether HFJV influence the frequency, severity, duration of gas embolism (GE) LLR. Methods Twenty-four anaesthetized piglets underwent were randomly assigned either normal frequency (NFV) (n=12 per group). During resection, standardized injury left hepatic was created increase risk GE. Haemodynamic respiratory variables monitored. Online monitoring transoesophageal echocardiography used. GE occurrence severity graded as 0 (none), 1 (minor), 2 (major), depending on results. Results shorter group (P=0.008). However, no differences found between two groups embolism. Incidence Grade less than previous studies physiological responses variable. Conclusion shortened mean LLR feasible procedure. Individual unpredictable.

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