作者: Anders O. Grubb , Arne Forsgren
DOI:
关键词: IgD binding 、 Immunoglobulin D 、 Fc fragment 、 Serum samples 、 Hemophilus influenzae 、 Incubation 、 Neisseria catarrhalis 、 Biology 、 Microbiology 、 M Components
摘要: Forty-four bacterial strains belonging to 19 species were tested for their IgD-binding capacity by incubation with radiolabeled human IgD. A high binding of IgD Neisseria catarrhalis and Hemophilus influenzae a moderate streptococci the groups A, C, G found. Two N. ability bind selectively in normal pooled serum three samples M components found possess this property. Binding studies Fab Fc fragments indicated that mainly but not exclusively involves CH1 region molecule.