Many Bacterial Species Bind Human IgD

作者: Anders O. Grubb , Arne Forsgren

DOI:

关键词: IgD bindingImmunoglobulin DFc fragmentSerum samplesHemophilus influenzaeIncubationNeisseria catarrhalisBiologyMicrobiologyM Components

摘要: Forty-four bacterial strains belonging to 19 species were tested for their IgD-binding capacity by incubation with radiolabeled human IgD. A high binding of IgD Neisseria catarrhalis and Hemophilus influenzae a moderate streptococci the groups A, C, G found. Two N. ability bind selectively in normal pooled serum three samples M components found possess this property. Binding studies Fab Fc fragments indicated that mainly but not exclusively involves CH1 region molecule.

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