Peroxisomal-protein import: is it really that complex?
作者： Stephen J. Gould , Cynthia S. Collins
DOI: 10.1038/NRM807
关键词: Peroxisome membrane 、 Peroxisome 、 Peroxisomal enzyme 、 Biochemistry 、 Cytoplasm 、 Enzyme 、 Organelle 、 Cell biology 、 Biology
摘要: Peroxisomal enzymes are synthesized in the cytoplasm and imported post-translationally across peroxisome membrane. Unlike other organelles with a sealed membrane, peroxisomes can import folded enzymes, they seem to lack intraperoxisomal chaperones. Here, we propose mechanistic model for early steps peroxisomal-matrix-enzyme import, which might help explain unusual features of this process.
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