Physical, emotional, and social health differences between posttreatment young adults with cancer and matched healthy controls

摘要: BACKGROUND Young adults (YAs; ages 18-39 years) with cancer face interrupted developmental milestones and increased stressors that can adversely influence psychosocial adjustment. Transitioning from active treatment to posttreatment survivorship be particularly challenging. The purpose of this study is describe the health-related quality life (HRQL) psychological adaptation YAs after treatment, relative young without cancer. METHODS Three cohorts mixed diagnoses (N = 120, 0-12 months treatment; N = 102, 13-24 N = 113, 25-60 combined M = 31.8 years old, sex = 68% women) an age-, education-, sex-, partner status–matched group healthy control participants (HCs; N = 335) were recruited via online research panel. All completed measures assessing demographic clinical characteristics, HRQL (physical, emotional, social, spiritual), (anxiety, depression, positive affect, posttraumatic growth). Measure content was slightly modified for applicability HCs a history. RESULTS Multivariate analysis covariance found significant main effect (YAs versus HCs) group-by-cohort interaction. reported poorer physical (P = .005, d = .22) emotional well-being (P = .011, d = .20) but better social (P < .001, d = .49). comparatively stable scores (P = .74) growth compared HCs, who greater across (P = .01, d = 16). CONCLUSIONS Findings underscore negative sequelae highlight need comprehensive assessment among YA survivors cancer. A matched, HC allows placed in context, enabling more precise determination impact on YAs. Cancer 2014;120:2247–2254. © 2014 American Society.