Glioma surgery in eloquent areas: can we preserve cognition?

摘要: Cognitive preservation is crucial in glioma surgery, as it an important aspect of daily life functioning. Several studies claimed that surgery eloquent areas possible without causing severe cognitive damage. However, this conclusion was relatively ungrounded due to the lack extensive neuropsychological testing homogenous patient groups. In study, we aimed elucidate short-term and long-term effects on cognition by identifying all who conducted tests preoperatively postoperatively patients. We systematically searched electronical databases Embase, Medline OvidSP, Web Science, PsychINFO PubMed, Cochrane, Google Scholar, Scirius Proquest at performance patients postoperatively. included 17 with assessing domains: language, memory, attention, executive functions and/or visuospatial abilities. Language domain most frequently examined. Immediately postoperatively, except one, found deterioration one or more domains. longer term (3–6/6–12 months postoperatively), following showed both recovery compared preoperative level: naming verbal fluency (language), word learning (memory) Trailmaking B (executive functions). level after a certain extent; however, results are too arbitrary draw definite conclusions not investigated More postoperative follow-up for change necessary better understanding conclusive cognition.