HUMAN GASTRIC ATONY WITH TACHYGASTRIA AND GASTRIC RETENTION

摘要: Abstract A 5-month-old white male developed gastric retention unrelieved by either pyloromyotomy or gastrojejunostomy. The pattern of electrical activity in the wall stomach recorded at a third operation was consistent with an ectopic distal antral pacemaker generating cycles (pacesetter potentials, action control potentials) rapid frequency 4.7 per min (tachygastria). pressure increased from 1 cm H 2 O to only 5 as distended 600 ml, no further increase after 0.6 mg urecholine given subcutaneously. Resection three-fourths and gastrojejunostomy when patient year old allowed him resume oral intake without vomiting progressive weight gain. circular smooth muscle cells corpus antrum, tested vitro using intracellular electrodes, generated frequencies 20 min, respectively. plateau component spontaneous which regulates contractile activity, small absent both corporal cells, size not pentagastrin acetylcholine doses suprathreshold for healthy muscle. Our conclusion is that decreased diminished sensitivity appropriate stimuli caused this patient's retention.