Prevalence of Gastroesophageal Reflux Disease in Patients With Nontuberculous Mycobacterial Lung Disease

摘要: Background Knowledge of the relationship between respiratory disorders and gastroesophageal reflux disease (GERD) is increasing. However, association GERD pulmonary caused by nontuberculous mycobacteria (NTM) has not been studied in detail. We investigated prevalence patients with nodular bronchiectatic form NTM lung disease. Methods Fifty-eight underwent ambulatory 24-h esophageal pH monitoring. Of 58 patients, 27 were identified as having Mycobacterium avium complex infection (15 intracellulare 12 M ), 31 had abscessus infection. Results The was 26% patients). Only 27% (4 15 patients) typical symptoms. No statistically significant differences found those without regard to age, sex, body mass index, or function test results. more likely have a sputum smear that positive for acid-fast bacilli (12 80%), compared (19 43 44%) [p = 0.033]. In addition, bronchiectasis bronchiolitis observed lobes than (p 0.008 p 0.005, respectively). Conclusions Patients high increased acid exposure, usually