Epidemic of meningococcal meningitis in Bamako, Mali: epidemiological features and analysis of vaccine efficacy.

摘要: Abstract Many studies have demonstrated the efficacy of meningococcal vaccine in non-epidemic meningitis, but few examined its epidemic conditions. The effects on course a meningitis Bamako, Mali, between January and April, 1981, were studied. was effective limiting further spread epidemic. attack rate among those who received lower than that unvaccinated (0·7/10 000 vs 4·7/10 000), case-fatality vaccinees whom developed unvaccinated. Routine vaccination against Africa may be impracticable owing to cost, relatively short duration effectiveness, irregular occurrence epidemics. Vaccination early an epidemic, however, appears useful practicable method disease.