Pyoderma gangrenosum with necrotizing sclerokeratitis after cataract surgery.

摘要: A 78-year-old man who had uneventful extracapsular cataract extraction in the left eye 3 months earlier developed pyoderma gangrenosum (PG)–associated peripheral ulcerative keratitis (PUK) after suture removal. The patient a 13-year history of PG associated with monoclonal immunoglobulin-A gammopathy. He presented extensive, painful PUK at incision site, descemetocele and high risk for perforation. Fibrin glue tissue adhesive was used to stabilize corneal ulcer as an adjunct topical systemic treatment. been treated tapering doses prednisone cyclophosphamide (50 mg/day). High-dose human intravenous immunoglobulin (0.4 mg/kg/d 4 days) administered. healed 1 month later loss visual acuity. To our knowledge, this is first reported case PG-associated sclerokeratitis following surgery. Early recognition rare ocular localization important institute appropriate therapy.