Anti-cancer therapeutic compounds

摘要: A treatment for cancer, and in particular, of therapeutic compounds which block the ability cytokines chemokines to promote metastasis malignant cells. The compound comprises a carboxylated and/or sulfated oligosaccharide, preferably substantially purified form, is heparin or heparan-sulfate derived saccharide compound. In one embodiment present invention, carbohydrate oligosaccharide has molecular weight no more than about 3000 daltons, lying range 400 2000 most between 1100 daltons. Generally, substances invention inhibit tumor cell migration, as determined by biological assays, comprise molecules various sugar units basic unit activity associated with disaccharide. However, larger chains up 10 units, containing disaccharide can also function such activity.