Palladium-Catalyzed α-Arylation of Esters and Amides under More Neutral Conditions

作者: Takuo Hama , Xiaoxiang Liu , Darcy A. Culkin , John F. Hartwig

DOI: 10.1021/JA036792P

关键词: RacemizationChemistryBromideKeteneSilylationImideArylCatalysisOrganic chemistryMedicinal chemistryTrimethylsilyl

摘要: … To determine if the more neutral conditions generated a kinetic ratio of diastereomers, we … Thus, the conditions for the α-arylation of the silyl enolates are neutral enough to prevent …

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