The effect of hypophysectomy and growth hormone on S35 fixation in cartilage.

摘要: THE studies of Dziewiatkowski et al. (1949), Layton (1952) and (1952, 1953) have demonstrated that radioactive sulfur, S35, is readily fixed into connective tissue, eapecially cartilage, man, rats mice. Cartilage many times more active in rate sulfur fixation than are other tissues. By isolating chondroitin sulf ate S35O4-, intraperitoneally, (1951) Bostrom showed S35 incorporated sulfate, the essential polysaccharide cartilage. This uptake a vital process since boiled cartilage shows no such activity nor there noteworthy when Na2S35O4 added to pure sulfuric acid alone (Bostrom Mansson, 1952). In view notable influence growth hormone pituitary body on (Becks al., 1949) knowledge effects this principle metabolism becomes essential.