Antituberculosis agents. I. Alpha-(5-(2-Furyl)-1,2,4-triazol-3-ylthio) acethydrazide and related compounds.

作者: I. Mir , M.T. Siddiqui , A. Comrie

DOI: 10.1016/S0040-4020(01)98732-0

关键词: Medicinal chemistryAlpha (ethology)Chemistry

摘要: Abstract α-[5-(2-Furyl)-1,2,4-triazol-3-ylthio] acethydrazide, δ-Allyl-α-[5-(2-furyl)-1,2,4-triazol-3-ythio-acet] thiosemicarbazide, α-[5-(2-furyl)-1,2,4-triazol-3-ylthio] acethydroxamic add and other related compounds have been prepared α-15-(2-furyl)-1,2,4-triazol-3-ylthiol acethydrazide has significant activity against Myco. tuberculosis .

参考文章(1)
H. HERBERT FOX, Synthetic Tuberculostats. XII. Structure of the Reaction Product of Isoniazid and Formaldehyde Journal of Organic Chemistry. ,vol. 23, pp. 468- 472 ,(1958) , 10.1021/JO01097A037