Biochemical Toxicity and Potential Detoxification Mechanisms in Earthworms Eisenia fetida Exposed to Sulfamethazine and Copper.

作者: Hong Rong , Chengrun Wang , Haitao Liu , Min Zhang , Yueting Yuan

DOI: 10.1007/S00128-020-02927-5

关键词: Reactive oxygen speciesSuperoxide dismutaseProtein oxidationDetoxificationBiochemistryGlutathione peroxidaseChemistryGlutathioneEisenia fetidaCatalase

摘要: The present study investigated the biochemical toxicity and potential detoxification mechanisms in earthworms Eisenia fetida exposed to sulfamethazine (SMZ) (7.5, 15 30 mg kg-1) either alone or combination with Copper (Cu) (100 soil. results showed that increasing concentrations of SMZ soil activated superoxide dismutase, catalase glutathione peroxidase isozymes, suggesting reactive oxygen species (ROS) burst earthworms. Treatment Cu separately caused protein oxidation damage, elevating synthesis ubiquitin, 20S proteasome, cytochrome P450 (CYP450), heat shock 70 (HSP70). Such treatments also induced activities proteases, endoproteinase (EP) S-transferases (GSTs). suggested ubiquitin-20S EP HSP70 were involved degradation remediation oxidatively damaged proteins. Elevated levels CYP450 GSTs participated

参考文章(37)
Yutaka Ogamino, Yoshio Sugaya, Shigehisa Hatakeyama, Refinement of OECD test guideline 222 for reproduction testing of Eisenia fetida (earthworm) with the fungicide benomyl as a reference chemical Japanese journal of environmental toxicology. ,vol. 11, pp. 157- 169 ,(2008) , 10.11403/JSET.11.157
Carmen Garcı́a-Limones, Ana Hervás, Juan A Navas-Cortés, Rafael M Jiménez-Dı́az, Manuel Tena, Induction of an antioxidant enzyme system and other oxidative stress markers associated with compatible and incompatible interactions between chickpea (Cicer arietinum L.) and Fusarium oxysporum f. sp.ciceris Physiological and Molecular Plant Pathology. ,vol. 61, pp. 325- 337 ,(2002) , 10.1006/PMPP.2003.0445
William H. Habig, William B. Jakoby, Assays for differentiation of glutathione S-transferases. Methods in Enzymology. ,vol. 77, pp. 398- 405 ,(1981) , 10.1016/S0076-6879(81)77053-8
W-D Kong, Y-G Zhu, B-J Fu, P Marschner, J-Z He, None, The veterinary antibiotic oxytetracycline and Cu influence functional diversity of the soil microbial community. Environmental Pollution. ,vol. 143, pp. 129- 137 ,(2006) , 10.1016/J.ENVPOL.2005.11.003
Ewa Gajewska, Maria SkŁodowska, Differential effect of equal copper, cadmium and nickel concentration on biochemical reactions in wheat seedlings. Ecotoxicology and Environmental Safety. ,vol. 73, pp. 996- 1003 ,(2010) , 10.1016/J.ECOENV.2010.02.013
Tilman Grune, Katrin Merker, Tobias Jung, Nicolle Sitte, Kelvin J.A. Davies, Protein oxidation and degradation during postmitotic senescence. Free Radical Biology and Medicine. ,vol. 39, pp. 1208- 1215 ,(2005) , 10.1016/J.FREERADBIOMED.2005.06.009
Warisara Lertpaitoonpan, Thomas B. Moorman, Say Kee Ong, Effect of Swine Manure on Sulfamethazine Degradation in Aerobic and Anaerobic Soils Water Air and Soil Pollution. ,vol. 226, pp. 81- ,(2015) , 10.1007/S11270-014-2286-1
Adam J. Book, Peizhen Yang, Mark Scalf, Lloyd M. Smith, Richard D. Vierstra, Tripeptidyl Peptidase II. An Oligomeric Protease Complex from Arabidopsis Plant Physiology. ,vol. 138, pp. 1046- 1057 ,(2005) , 10.1104/PP.104.057406
Chengrun Wang, Yuan Tian, Xiaorong Wang, Jinju Geng, Jinlin Jiang, Hongxia Yu, Chen Wang, Lead-contaminated soil induced oxidative stress, defense response and its indicative biomarkers in roots of Vicia faba seedlings Ecotoxicology. ,vol. 19, pp. 1130- 1139 ,(2010) , 10.1007/S10646-010-0496-X