Central nervous system stimulants and anorectic agents

摘要: Publisher Summary Reports on over- the- counter stimulants, amphetamines, xanthine derivatives, non-theophylline related respiratory anorectic agents, and nootropic agents are briefly mentioned. Moderate doses of caffeine (180 360 mg) were shown to cause significant hypokalemia in healthy volunteers. Phenylpropanolamine has caused behavioral disturbances, changes mood or even psychosis; the central stimulant effects a normal 25 mg anorexic dose seem be sufficient derangement certain individuals. Use is still being recommended for allergic vasomotor rhinitis as well management obesity. Propylhexedrine another example drug which sold valid purpose but misused by Cases psychosis, cardiac pulmonary problems, sudden death, have been reported following its abuse. Combined use methylphenidate narcotic analgesics proposed treatment cancer pain. Most problems arising with Pemoline relate CNS, organic complications including derangements liver function described both old young. Tolerability, toxicity correlation clinical symptoms serum theophylline level described. Sustained-release preparations usually tolerated. Aminophylline, derivative complex ethylenediamine, can exhibit adverse either components. Bamifylline new theophylline-like activity prolonged plasma half-life. It claimed safer than slow release Aminophylline. When cardiovascular enprophylline (which no adenosine receptor antagonism) (an antagonist) compared subjects, important differences found. Aminorex, Fenfluramine Mazindol anaorectic agents.