Small-molecule antioxidants in marine organisms: antioxidant activity of mycosporine-glycine

作者: Walter C. Dunlap , Yorihiro Yamamoto

DOI: 10.1016/0305-0491(95)00086-N

关键词: PhosphatidylcholineAutoxidationMycosporine-like amino acidOxidative stressAmino acidBiologyPorphyraBiochemistryGlycineAntioxidant

摘要: Abstract The antioxidant activities of aqueous extracts tissues from four different marine species containing mycosporine-like amino acids were examined by their peroxyl radical-trapping abilities using the phosphatidylcholine peroxidation inhibition assay. coral trout ( Plectropomus leopardus ) lens extract had low oxidation activity; Porphyra tenera and Lissoclinum patella moderately strong while Palythoa tuberculosa showed greatest activity tested; last two contained mycosporine-glycine. In these sample extracts, mycosporine-glycine was reactive to radicals whereas iminomycosporine-like acids, shinorine, porphyra-334, palythine, asterina-330 palythinol, oxidatively robust. Purified inhibited radical-initiated autoxidation phosphaditylcholine in a concentration-dependent manner. These results suggest that may function as biological organisms.

参考文章(53)
Lester Packer, Oxygen radicals in biological systems Academic Press. ,(1984)
Barry Halliwell, John M.C. Gutteridge, [4] Role of iron in oxygen radical reactions Methods in Enzymology. ,vol. 105, pp. 47- 56 ,(1984) , 10.1016/S0076-6879(84)05007-2
Michael P. Lesser, Wayne R. Stochaj, Photoadaptation and Protection against Active Forms of Oxygen in the Symbiotic Procaryote Prochloron sp. and Its Ascidian Host. Applied and Environmental Microbiology. ,vol. 56, pp. 1530- 1535 ,(1990) , 10.1128/AEM.56.6.1530-1535.1990
P. L. JOKIEL, Solar ultraviolet radiation and coral reef epifauna. Science. ,vol. 207, pp. 1069- 1071 ,(1980) , 10.1126/SCIENCE.207.4435.1069
E Cadenas, Biochemistry of oxygen toxicity. Annual Review of Biochemistry. ,vol. 58, pp. 79- 110 ,(1989) , 10.1146/ANNUREV.BI.58.070189.000455
Ned A. Porter, Mechanisms for the autoxidation of polyunsaturated lipids Accounts of Chemical Research. ,vol. 19, pp. 262- 268 ,(1986) , 10.1021/AR00129A001