Molecular studies of CGRP and the CGRP family of peptides in the central nervous system.

作者: Erica R Hendrikse , Rebekah L Bower , Debbie L Hay , Christopher S Walker

DOI: 10.1177/0333102418765787

关键词: Central nervous systemAmylinCalcitoninEndocrinologyNeurovascular bundleMigraineMedicinePeptideCalcitonin gene-related peptideInternal medicineAdrenomedullin

摘要: BackgroundCalcitonin gene-related peptide is an important target for migraine and other painful neurovascular conditions. Understanding the normal biological functions of calcitonin pe...

参考文章(162)
Johji Kato, Kazuo Kitamura, Bench-to-bedside pharmacology of adrenomedullin European Journal of Pharmacology. ,vol. 764, pp. 140- 148 ,(2015) , 10.1016/J.EJPHAR.2015.06.061
Leticia Figueira, Anita Israel, Role of cerebellar adrenomedullin in blood pressure regulation. Neuropeptides. ,vol. 54, pp. 59- 66 ,(2015) , 10.1016/J.NPEP.2015.07.003
Eric L Moore, Christopher A Salvatore, Targeting a family B GPCR/RAMP receptor complex: CGRP receptor antagonists and migraine. British Journal of Pharmacology. ,vol. 166, pp. 66- 78 ,(2012) , 10.1111/J.1476-5381.2011.01633.X
SJ Gibson, JM Polak, SR Bloom, IM Sabate, PM Mulderry, MA Ghatei, GP McGregor, JF Morrison, JS Kelly, RM Evans, Calcitonin gene-related peptide immunoreactivity in the spinal cord of man and of eight other species The Journal of Neuroscience. ,vol. 4, pp. 3101- 3111 ,(1984) , 10.1523/JNEUROSCI.04-12-03101.1984
M I Sabate, L S Stolarsky, J M Polak, S R Bloom, I M Varndell, M A Ghatei, R M Evans, M G Rosenfeld, Regulation of neuroendocrine gene expression by alternative RNA processing. Colocalization of calcitonin and calcitonin gene-related peptide in thyroid C-cells. Journal of Biological Chemistry. ,vol. 260, pp. 2589- 2592 ,(1985) , 10.1016/S0021-9258(18)89396-6
Jason M. Booe, Christopher S. Walker, James Barwell, Gabriel Kuteyi, John Simms, Muhammad A. Jamaluddin, Margaret L. Warner, Roslyn M. Bill, Paul W. Harris, Margaret A. Brimble, David R. Poyner, Debbie L. Hay, Augen A. Pioszak, Structural Basis for Receptor Activity-Modifying Protein-Dependent Selective Peptide Recognition by a G Protein-Coupled Receptor. Molecular Cell. ,vol. 58, pp. 1040- 1052 ,(2015) , 10.1016/J.MOLCEL.2015.04.018
Yanguo Hong, Debbie L Hay, Remi Quirion, David R Poyner, The pharmacology of adrenomedullin 2/intermedin. British Journal of Pharmacology. ,vol. 166, pp. 110- 120 ,(2012) , 10.1111/J.1476-5381.2011.01530.X
Sebastian GB Furness, Denise Wootten, Arthur Christopoulos, Patrick M Sexton, Consequences of splice variation on Secretin family G protein-coupled receptor function. British Journal of Pharmacology. ,vol. 166, pp. 98- 109 ,(2012) , 10.1111/J.1476-5381.2011.01571.X
Craig M. Bullock, Peter Wookey, Andrew Bennett, Ali Mobasheri, Ian Dickerson, Sara Kelly, Peripheral Calcitonin Gene-Related Peptide Receptor Activation and Mechanical Sensitization of the Joint in Rat Models of Osteoarthritis Pain Arthritis & Rheumatism. ,vol. 66, pp. 2188- 2200 ,(2014) , 10.1002/ART.38656
H Mulder, A Leckstrom, R Uddman, E Ekblad, P Westermark, F Sundler, Islet amyloid polypeptide (amylin) is expressed in sensory neurons The Journal of Neuroscience. ,vol. 15, pp. 7625- 7632 ,(1995) , 10.1523/JNEUROSCI.15-11-07625.1995