Role of neutrophils in a mouse model of halothane-induced liver injury.

作者: Qiang You , Linling Cheng , Timothy P. Reilly , Dale Wegmann , Cynthia Ju

DOI: 10.1002/HEP.21425

关键词: EndocrinologyMedicineRatónImmunologyHalothaneInnate immune systemNeutrophileInternal medicineHistologyTumor necrosis factor alphaLiver injuryNecrosis

摘要: … nor all possible mechanistic features of DILI. Another recently … and C57BL/6J (C) mice were ip injected with olive oil or 30 mmol… using an anti-Gr1 antibody. Infiltrated neutrophils were …

参考文章(38)
P M Hall, M J Cousins, C A Lunam, The pathology of halothane hepatotoxicity in a guinea-pig model: a comparison with human halothane hepatitis. British journal of experimental pathology. ,vol. 70, pp. 533- 541 ,(1989)
H JUAESCHKE, A FARHOOD, CW SMITH, Neutrophils contribute to ischemia/reperfusion injury in rat liver in vivo The FASEB Journal. ,vol. 4, pp. 3355- 3359 ,(1990) , 10.1096/FASEBJ.4.15.2253850
J.M. Neuberger, Halothane and Hepatitis Drug Safety. ,vol. 5, pp. 28- 38 ,(1990) , 10.2165/00002018-199005010-00004
Richard C. Lind, A. Jay Gandolfi, Pauline de la M. Hall, Age and gender influence halothane-associated hepatotoxicity in strain 13 guinea pigs. Anesthesiology. ,vol. 71, pp. 878- 884 ,(1989) , 10.1097/00000542-198912000-00011
Kevin D. Welch, Bo Wen, David R. Goodlett, Eugene C. Yi, Hookeun Lee, Timothy P. Reilly, Sidney D. Nelson, Lance R. Pohl, Proteomic identification of potential susceptibility factors in drug-induced liver disease. Chemical Research in Toxicology. ,vol. 18, pp. 924- 933 ,(2005) , 10.1021/TX050011B
Sylvia M. Furst, Dennis Luedke, Htoo-Htoo Gaw, Richard Reich, A.Jay Gandolfi, Demonstration of a Cellular Immune Response in Halothane-Exposed Guinea Pigs Toxicology and Applied Pharmacology. ,vol. 143, pp. 245- 255 ,(1997) , 10.1006/TAAP.1996.8093
Steven D. Cohen, Neil R. Pumford, Edward A. Khairallah, Kim Boekelheide, Lance R. Pohl, H.R. Amouzadeh, Jack A. Hinson, Selective Protein Covalent Binding and Target Organ Toxicity Toxicology and Applied Pharmacology. ,vol. 143, pp. 1- 12 ,(1997) , 10.1006/TAAP.1996.8074
L.R. Pohl, N.R. Pumford, J.L. Martin, Mechanisms, chemical structures and drug metabolism. European Journal of Haematology. ,vol. 57, pp. 98- 104 ,(2009) , 10.1111/J.1600-0609.1996.TB01654.X
Richard C. Lind, A Jay Gandolfi, Pauline de la M. Hall, Covalent binding of oxidative biotransformation intermediates is associated with halothane hepatotoxicity in guinea pigs. Anesthesiology. ,vol. 73, pp. 1208- 1213 ,(1990) , 10.1097/00000542-199012000-00019
Hawjyh Chiu, Jennie A. Brittingham, Debra L. Laskin, Differential induction of heme oxygenase-1 in macrophages and hepatocytes during acetaminophen-induced hepatotoxicity in the rat: effects of hemin and biliverdin. Toxicology and Applied Pharmacology. ,vol. 181, pp. 106- 115 ,(2002) , 10.1006/TAAP.2002.9409