CHAPTER 25 – Products of Cartilage Metabolism

作者: DANIEL-HENRI MANICOURT , JEAN-PIERRE DEVOGELAER , EUGENE J.-M. A. THONAR

DOI: 10.1016/B978-012088562-6/50026-1

关键词: Matrix (biology)CartilageBiochemistryCollagen typeAggrecanMaterials scienceBone matrixFunction (biology)Cartilage metabolismHomeostasis

摘要: This chapter discusses the major products of articular cartilage metabolism with special emphasis on those that are relevant as body fluid markers. It provides a brief review structure–function relationships matrix building blocks. The contains several molecules found in much higher concentrations than other tissues. attention aggrecan and collagen type II currently receiving potential markers specific metabolic alterations disease will likely extend to less abundant play key roles maintenance homeostasis. As understanding function these improves, so their irreversible destabilization collagenous meshwork or organization.

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