Noninvasive Transthoracic Low Frequency Ultrasound Augments Thrombolysis in a Canine Model of Acute Myocardial Infarction – Evaluation of the Extent of ST-Segment Resolution

作者: Yochai Birnbaum , Huai Luo , Shaul Atar , Michael C. Fishbein , Andrea V. Brasch

DOI: 10.1023/A:1011964904848

关键词: CardiologyMyocardial infarctionSurgeryST segmentMedicineInternal medicineThrombolysisElectrocardiographyTissue plasminogen activatorCoronary arteriesT-plasminogen activatorUltrasound

摘要: Background: Recently it has been demonstrated that transcutaneous delivery of ultrasound combined with tissue plasminogen activator (tPA) is more effective than tPA alone in recanalizing acutely thrombosed canine coronary arteries. In the present study, we investigated incidence partial (≥50%) and complete (≥70%) ST-segment elevation resolution precordial leads dogs experimental acute myocardial infarction were treated or combination noninvasive high-intensity low frequency (27[emsp3 ]kHz) ultrasound.

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