Evaluating quality of life in epilepsy: The role of screening for adverse drug effects, depression, and anxiety.
作者： Jean-Arthur Micoulaud-Franchi` , Fabrice Bartolomei , Roderick Duncan , Aileen McGonigal
DOI: 10.1016/J.YEBEH.2017.07.016
关键词: Generalized anxiety disorder 、 Mini-international neuropsychiatric interview 、 Cronbach's alpha 、 Worry 、 Quality of life 、 Clinical psychology 、 Psychiatry 、 Major depressive disorder 、 Psychometrics 、 Psychology 、 Anxiety
摘要: Abstract Objective The objective of this study was to evaluate the contribution validated screening tools for antiepileptic drug (AED) adverse effects, depression, and anxiety measure quality life (QoL) in people with epilepsy (PWE). Methods Patients a tertiary service were screened (using QOLIE-31), major depressive disorder (MDD) (NDDI-E), generalized (GAD) (GAD-7), AED effects (AEP). Mini International Neuropsychiatric Interview (MINI) module also performed. For AEP validation French, internal structural validity analyzed. Dimensional (NDDI-E GAD-7 scores) categorical (MDD GAD) analyses performed investigate interactions between QoL AEP. Results A total 132 (87 females) subjects included. French version demonstrated satisfactory psychometric properties (Cronbach's α 0.87). Correlations NDDI-E, GAD-7, AEP, QOLIE-31 scores high, significant all subscales QOLIE-31; no effect seizure-related variables seen. Some sex differences found, mean score higher females. Age, sex, accounted 61% variance scores. Differential seen on subscales: strongly correlated subscales; more “Seizure Worry”; NDDI-E “Energy-Fatigue”; both “Emotional Well-Being”. Categorical analysis groups MDD alone, GAD MDD + GAD, neither nor showed scores, MDD + GAD showing most poorest QoL. Significance combination depression (AEP) has strong power evaluating PWE. Coexisting MMD associated highest
sci-hub.se 参考文章(42)
Chiara Luoni, Francesca Bisulli, Maria Paola Canevini, Giovambattista De Sarro, Cinzia Fattore, Carlo Andrea Galimberti, Giuliana Gatti, Angela La Neve, Giancarlo Muscas, Luigi Maria Specchio, Salvatore Striano, Emilio Perucca, SOPHIE Study Group, None, Determinants of health-related quality of life in pharmacoresistant epilepsy: results from a large multicenter study of consecutively enrolled patients using validated quantitative assessments. Epilepsia. ,vol. 52, pp. 2181- 2191 ,(2011) , 10.1111/J.1528-1167.2011.03325.X
Andres M. Kanner, John J. Barry, Frank Gilliam, Bruce Hermann, Kimford J. Meador, Depressive and anxiety disorders in epilepsy: Do they differ in their potential to worsen common antiepileptic drug-related adverse events? Epilepsia. ,vol. 53, pp. 1104- 1108 ,(2012) , 10.1111/J.1528-1167.2012.03488.X
David M. Ficker, Quality of Life in Epilepsy: The Key Importance of the Interictal State Epilepsy and the interictal state. pp. 1- 6 ,(2015) , 10.1002/9781118951026.CH1
Rumyana Kuzmanova, Irina Stefanova, Irena Velcheva, Katerina Stambolieva, Translation, cross-cultural adaptation, and validation of the Bulgarian version of the Liverpool Adverse Event Profile Epilepsy & Behavior. ,vol. 39, pp. 88- 91 ,(2014) , 10.1016/J.YEBEH.2014.08.124
Jean-Arthur Micoulaud-Franchi, Gérald Barkate, Agnès Trébuchon-Da Fonseca, Lisa Vaugier, Martine Gavaret, Fabrice Bartolomei, Aileen McGonigal, One step closer to a global tool for rapid screening of major depression in epilepsy: Validation of the French NDDI-E Epilepsy & Behavior. ,vol. 44, pp. 11- 16 ,(2015) , 10.1016/J.YEBEH.2014.12.011
Louis St, K Erik, Minimizing AED Adverse Effects: Improving Quality of Life in the Interictal State in Epilepsy Care Current Neuropharmacology. ,vol. 7, pp. 106- 114 ,(2009) , 10.2174/157015909788848857
Li Yue, Pei-min Yu, De-hao Zhao, Dong-yan Wu, Guo-xing Zhu, Xun-yi Wu, Zhen Hong, Determinants of quality of life in people with epilepsy and their gender differences Epilepsy & Behavior. ,vol. 22, pp. 692- 696 ,(2011) , 10.1016/J.YEBEH.2011.08.022
Dale C. Hesdorffer, Elisa Baldin, Rochelle Caplan, Anne T. Berg, How do we measure psychiatric diagnoses? Implications of the choice of instruments in epilepsy Epilepsy & Behavior. ,vol. 31, pp. 351- 355 ,(2014) , 10.1016/J.YEBEH.2013.10.001
Mar Carreño, Antonio Donaire, Mercè Falip, Iratxe Maestro, Santiago Fernández, Antonio Gil Nagel, Jose Serratosa, Javier Salas, César Viteri, Jordi Llorens, Eva Baró, Validation of the Spanish version of the Liverpool Adverse Events Profile in patients with epilepsy Epilepsy & Behavior. ,vol. 15, pp. 154- 159 ,(2009) , 10.1016/J.YEBEH.2008.11.016
Jana E Jones, Bruce P Hermann, John J Barry, Frank G Gilliam, Andres M Kanner, Kimford J Meador, Rates and risk factors for suicide, suicidal ideation, and suicide attempts in chronic epilepsy Epilepsy & Behavior. ,vol. 4, pp. 31- 38 ,(2003) , 10.1016/J.YEBEH.2003.08.019