75-jährige Patientin mit Pleuraerguss und gastralen Metastasen eines wenig differenzierten Karzinoms
作者： E. Roeb , T. Dreyer , D. Steiner , A. Bräuninger , S. Gattenlöhner
DOI: 10.1007/S00108-012-3184-5
关键词: Gynecology 、 Medicine
摘要: Bei einer 75-jahrigen Patientin mit Pleuraerguss wurde die seltene Entitat eines adenoid-zystischen Karzinoms zunachst als Metastase im Magen entdeckt. etwa 20% der Patienten diesem Karzinom werden Fernmetastasen diagnostiziert. Fur das initiale Staging haben sich in den letzten Jahren Positronenemissionstomographie (PET) und PET-Computertomographie (CT) etabliert. In Halfte Falle ist Tumorgewebe t(6;9)(q22–23;p23–24)-Translokation nachweisbar, fur verschiedene Varianten von MYB-NFIB-Fusionstranskripten codiert. Die molekularpathologische Diagnostik erleichtert korrekte Diagnosestellung Identifizierung des Primartumors.
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