Molecular Adjuvants Based on Nonpyrogenic Lipophilic Derivatives of norAbuMDP/GMDP Formulated in Nanoliposomes: Stimulation of Innate and Adaptive Immunity

作者: Pavlína Turánek Knotigová , Daniel Zyka , Josef Mašek , Anna Kovalová , Michal Křupka

DOI: 10.1007/S11095-014-1516-Y

关键词: Innate immune systemAdjuvantChemistryImmunityLiposomeAcquired immune systemPharmacologyMuramyl dipeptideImmunologyAntigenIn vivo

摘要: … Another MDP analogue (MTP-PE, Mifamurtide) was … Severe hearing loss occured in 12% of the Mifamurtide-treated … well established, much more stable platform for the formulation and …

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