A cryobank as an attribute of omics technologies

作者: A.A. Sazanov , Kh.Kh. Erganokov , E. Pfeifer

DOI: 10.18097/PBMC20176305428

关键词: AnnotationData scienceEnd userStandardizationBiobankBiological materialsComputer scienceBioinformaticsPersonalized medicineOmics technologiesPopulation

摘要: Biobanks are systematic and annotated collections of biological samples based on the system standard operating procedures (SOP) corresponding to recommendations International Society for Biological Environmental Repositories (ISBER). Standardization conditions obtaining, processing, storage providing an end user crucial in activities biobank. The attributes biobanks include common principles labeling annotation using specialized software, automated monitoring conditions, registration biosamples. Cryobanks maintained at from -196°C -150°C that provide better cell viability highest preservation molecules. Cryobanking is most essential part infrastructure population personalized medicine, pharmaceuticals biopharmacology, conservation rare endangered species, as well biotechnology general. Next Generation Biobanking, a concept especially designed omics technologies, involves annotating many biomarkers Sequencing techniques, collecting material same patient different time points (for example, stages disease, before after operation, periods therapy) with detailed physiological, biochemical clinical data. Epigenetic studies (DNA methylation, microRNA, etc.), bioinformatic data analysis great importance activity Biobanking. Such should function new ethical post-genomic era.

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