Copper(I)-catalyzed synthesis of thienopyrazoloquinazolinone derivatives under ligand-free conditions
作者： Wen-Ting Zhang , Dong-Sheng Chen , Mei-Mei Zhang , Xiang-Shan Wang
DOI: 10.1007/S11164-016-2497-8
关键词: Ligand 、 Condensation 、 Copper 、 Chemistry 、 Ullmann reaction 、 Medicinal chemistry 、 Catalysis 、 General chemistry
摘要: A series of fused tetracyclic thieno[3′,2′:3,4]pyrazolo[5,1-b]quinazolin-6(4H)-one derivatives were synthesized by reaction 2-aminobenzohydrazide and 3-bromothiophene-2-carbaldehyde in good yields. The includes subsequent condensation, cyclization, CuBr-catalyzed Ullmann-type under ligand-free conditions.
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