Anaphylactoid reactions during hemodialysis on AN69 membranes in patients receiving ACE inhibitors
作者： Christian Tielemans , Philippe Madhoun , Michele Lenaers , Liliane Schandene , Michel Goldman
DOI: 10.1038/KI.1990.301
关键词: Bradykinin 、 Pharmacology 、 Enzyme inhibitor 、 Anaphylaxis 、 Hemodialysis 、 Enalapril 、 Internal medicine 、 Angiotensin-converting enzyme 、 Toxicity 、 Medicine 、 Endocrinology 、 Peptide hormone 、 Nephrology
摘要: We report five life-threatening anaphylactoid reactions occurring within the very first minutes of hemodialysis on polyacrylonitrile (AN69) capillary dialyzers in three patients receiving ACE inhibitors. Such were not observed either treated with inhibitors but dialyzed other membranes (N = 9), nor AN69 who did receive 19). These could be due to bradykinin accumulation, as a result both increased synthesis--by interaction blood polymer--and catabolism blockade by
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