The effects of different inspired oxygen fractions on gas exchange and Tei‐index of myocardial performance in propofol‐anesthetized dogs
作者： Patrícia C Ferro Lopes , Newton Nunes , Marlos G Sousa , Celina TD Nishimori , Roberta Carareto
DOI: 10.1111/VAA.12074
关键词: Isovolumic relaxation time 、 Mean arterial pressure 、 Oxygen tension 、 Propofol 、 Cardiac index 、 Oxygen 、 Heart rate 、 Anesthesia 、 Medicine 、 Respiratory system
摘要: Abstract Objective To evaluate the influence of different inspired oxygen fractions (FiO 2 ) on pulmonary exchange and Tei‐index myocardial performance in propofol‐anesthetized dogs. Study design Prospective crossover, randomized, experimental trial. Animals Eight adult dogs weighing 8.6 ± 1.8 kg. Methods The animals were anesthetized five occasions, receiving either an FiO = 1.0 (F100), 0.8 (F80), 0.6 (F60), 0.4 (F40) or 0.21 (F21). Propofol was used for induction (6.45 0.69 mgkg −1 IV) followed by a continuous rate infusion (CRI, 0.7 minute ). breathed spontaneously. initial measurements arterial partial pressures (PaO carbon dioxide (PaCO ), hemoglobin saturation (SaO heart (HR), mean pressure (MAP), cardiac index (CI), stroke (SI), pre‐ejection period (PEP) left ventricular ejection time (LVET) performed 30 minutes after beginning CRI (T0) then, at 15‐minute intervals (T15–T60). From these following calculated; alveolar (PAO alveolar‐arterial gradient (AaDO pressure/inspired fraction ratio /FiO arterial‐to‐alveolar tension /PAO respiratory (RI), delivery ( D ˙ O PEP/LVET ratio, isovolumic relaxation (IVRT) Tei‐index. Results At T30, PaCO F100 higher than F21. AaDO greater other treatments. PaO F21 lower F80 T0 F60 T15. T15, RI F80, F60. F40 F21, which F40. Conclusion cardiovascular parameters are not affected . Clinical Relevance An impaired efficiency.
sci-hub.se 参考文章(28)
David J. Durand, Interpretation of Blood Gases Manual of Neonatal Respiratory Care. pp. 159- 166 ,(2012) , 10.1007/978-1-4614-2155-9_19
June A. Boon, Manual of Veterinary Echocardiography ,(1998)
David H. Spodick, Yoshinori L. Doi, Richard L. Bishop, Tetsuo Hashimoto, Systolic time intervals reconsidered The American Journal of Cardiology. ,vol. 53, pp. 1667- 1670 ,(1984) , 10.1016/0002-9149(84)90599-X
B. Ditollo, O. Casalonga, M. Rotondaro, C. Lightowler, J. Barrios, M. Bartolomeo, Determinación del valor normal del índice de Tei del ventrículo izquierdo en caninos sanos InVet. ,vol. 8, pp. 41- 49 ,(2006)
Donald F. Morrison, Multivariate statistical methods Published in <b>1976</b> in New York NY) by McGraw-Hill. ,(1976)
Janet Aldrich, Kate Hopper, Lynelle Johnson, Steve Haskins, Successful ventilatory management of post‐anesthetic airway collapse and hypoxemia in a dog Journal of Veterinary Emergency and Critical Care. ,vol. 12, pp. 105- 112 ,(2002) , 10.1046/J.1435-6935.2002.00024.X
Andrew A. Pellett, William G. Tolar, Darrin G. Merwin, Edmund K. Kerut, The Tei Index: Methodology and Disease State Values Echocardiography-a Journal of Cardiovascular Ultrasound and Allied Techniques. ,vol. 21, pp. 669- 672 ,(2004) , 10.1111/J.0742-2822.2004.04052.X
Ian A. Herrick, Lois K. Champion, Alison B. Froese, A clinical comparison of indices of pulmonary gas exchange with changes in the inspired oxygen concentration Canadian Journal of Anaesthesia-journal Canadien D Anesthesie. ,vol. 37, pp. 69- 76 ,(1990) , 10.1007/BF03007487
Peter D. Slinger, Nunn???s Applied Respiratory Physiology, 6th ed. Anesthesia & Analgesia. ,vol. 104, pp. 1315- 1316 ,(2007) , 10.1213/01.ANE.0000263678.14958.4E
Antonio JA Aguiar, Stelio PL Luna, Valéria NLS Oliva, Flávia R Eugênio, Gladys B Castro, None, Continuous infusion of propofol in dogs premedicated with methotrimeprazine Veterinary Anaesthesia and Analgesia. ,vol. 28, pp. 220- 224 ,(2001) , 10.1046/J.1467-2987.2001.00048.X