HER2 Assessment in Upper Gastrointestinal Tract Adenocarcinoma: A Practical, Algorithmic Approach.
作者： Jon M. Davison , Reetesh K. Pai
DOI: 10.1016/J.PATH.2013.05.001
关键词: Upper gastrointestinal 、 Medicine 、 Esophageal adenocarcinoma 、 Gastroesophageal Junction 、 Gastric adenocarcinoma 、 Internal medicine 、 Trastuzumab 、 Gastroenterology 、 Adenocarcinoma 、 Localized disease 、 Chemotherapy
摘要: Gastric and gastroesophageal junction adenocarcinomas constitute a major health problem. For localized disease, adjuvant treatment is multidisciplinary usually includes combination of surgery, radiation chemotherapy. Recently, trastuzumab (Herceptin) has been approved for the metastatic upper gastrointestinal (GI) tract (gastric, esophageal, gastroesophageal) adenocarcinomas. The purpose this review to provide pathologists with practical guidance in HER2 assessment GI order accurately identify patients eligible therapy.
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