Heme A biosynthesis.
作者： Lars Hederstedt
DOI: 10.1016/J.BBABIO.2012.03.025
关键词: Cytochrome 、 Conjugated protein 、 Heme 、 Stereochemistry 、 Biochemistry 、 Aerobic bacteria 、 Heme A 、 Hemeprotein 、 Biology 、 Heme B 、 Respiratory enzyme
摘要: Respiration in plants, most animals and many aerobic microbes is dependent on heme A. This a highly specialized type of found as prosthetic group cytochrome a-containing respiratory oxidases. Heme A differs structurally from B (protoheme IX) by the presence hydroxyethylfarnesyl instead vinyl side at C2 position formyl methyl C8 porphyrin macrocycle. synthase catalyzes formation poorly understood heme-containing membrane bound atypical monooxygenase. review presents our current understanding synthesis molecular level mitochondria bacteria. article part Special Issue entitled: Biogenesis/Assembly Respiratory Enzyme Complexes.
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