Episome-mediated transfer of drug resistance in Enterobacteriaceae. III. Transduotion of resistance factors.

摘要: Watanabe, Tsutomu (Keio University, Tokyo, Japan), and Toshio Fukasawa. Episome-mediated transfer of drug resistance in Enterobacteriaceae. III. Transduction factors. J. Bacteriol. 82:202-209. 1961.-Transmissible multiple Enterobacteriaceae, which includes to streptomycin (SM), chloramphenicol (CM), tetracycline (TC), sulfonamide (Su), was found be transduced the systems Salmonella typhimurium strain LT-2 with phage P-22 Escherichia coli K-12 P1kc. No linked chromosomal markers factors have so far been substrains K-12. The transductants were all able their by conjugation, whereas a majority those could not conjugation. segregated rarely consistently LT-2. Defective transferred conjugation thus made resistant four drugs only had introduced none transduced. patterns segregation transduction suggested that they are located following sequence; Su-----Sm-----Cm-----Tc, assumed carried an episome "resistance factor" is considered at distal end Tc.