Natural 1,3‐Dipolar Cycloadditions
作者： Martin Baunach , Christian Hertweck
关键词: Cofactor 、 Natural product 、 Prenyl transferase 、 Organic chemistry 、 Biosynthesis 、 Azomethine ylide 、 Ubiquinone Biosynthesis 、 Stereochemistry 、 Decarboxylation 、 Flavin group 、 Chemistry
摘要: [3+2] in the wild: Biomimetic natural product syntheses and theoretical considerations have indicated that 1,3-dipolar cycloadditions take place nature. Now, structure, biosynthesis, function of a heavily modified prenylated flavin cofactor been elucidated. In azomethine ylide form, it undergoes with aromatic acids promotes their decarboxylation.
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