Enamel Tissue Engineering

摘要: Dental scientists are eagerly embracing regenerative medicine using tissue engineering technology. Enamel, one component of teeth, is the hardest in body. It cannot regenerate by itself, because it formed a layer ameloblasts that lost time tooth crown has completely formed. Although enamel spent during lifetime, vulnerable to wear, damage, and decay. For these reasons, development technique produces artificially-grown culture transplantation techniques strongly desired. In this chapter we report new for culturing organ epithelial cells have capacity produce enamel. After completion formation crown, which composed an enamel-dentin complex, root begins. Generally, no or generated from after Epithelial cell rests Malassez, derived Hertwig’s sheath fragments, located periodontal ligament, recently reported also capable production same technique. including Malassez can continue proliferate when they subcultured on top feeder cells. These were placed onto collagen sponge scaffolds along with dental pulp constructs transferred into abdominal cavities rats. When removed 4 weeks, was observed scaffolds. The key finding study even multiple divisions, retained Now be system, next step will combine tissue-engineered injured original teeth.