Betamethasone in plus phenobarbitone prior to hepatobiliary scintigraphy increases diagnostic accuracy in infants with jaundice.
作者： D. K. Gupta , A. R. Charles , M. Srinivas , S. Dave , C. S. Bal
DOI: 10.1007/BF02722353
关键词: Jaundice 、 Neonatal hepatitis 、 Scintigraphy 、 Betamethasone 、 Internal medicine 、 Medicine 、 Excretion 、 Gastroenterology 、 Biliary atresia 、 Hepatitis 、 Biliary tract
摘要: Objective. In the diagnostic work up of child with neonatal obstructive cholangiopathy (NOC), hepatobiliary scintigraphy (HBS) determines need for peroperative cholangiography (POC). Traditionally, phenobarbitone is recommended to prime liver HBS. This retrospective study was designed evaluate whether addition betamethasone (BM) alters accuracy HBS in distinguishing hepatitis (NH) from extra hepatic biliary atresia (EHBA).Methods : Between 1993 – 1999, 202 patients presented NOC and this not as a prospective randomized clinical trial. Of these, 126 had received Phenobarbitone (Group I) remaining 76 II) BM PB dose 5 mg/k/d 2.2 respectively 7 days prior HBS.Results Retrospective analysis revealed that, Group I, 41 showed excretion 85 did show any radiopharmaceutical latter underwent POC which that 31 (36%) them patent tract. group II, 32 44 undergone POC, only 8 (18%) The percentages false positives (36% vs 18%) statistically significant (p<0.03).Conclusion Addition increases would lead decreased distinguish NH EHBA.
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