Multiplexed proteomics mapping of yeast RNA polymerase II and III allows near-complete sequence coverage and reveals several novel phosphorylation sites.

作者: Shabaz Mohammed , Kristina Lorenzen , Robert Kerkhoven , Bas van Breukelen , Alessandro Vannini

DOI: 10.1021/AC7024283

关键词: ProcessivityRNAChemistryComplete sequenceNucleic acidBiochemistryMolecular biologyRNA polymerase IIRNA polymerase IIIPolymeraseProteomics

摘要: The multisubunit RNA polymerases (Pols) II and III synthesize mainly eukaryotic mRNAs tRNAs, respectively. Pol are protein complexes consisting of 12 17 subunits. Here we ana...

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