Pyruvate Inhibition of Lactate Dehydrogenase Activity in Human Tissue Extracts
作者： A. W. Skillen , S. A. Siddiqui , A. L. Latner
DOI: 10.1126/SCIENCE.154.3748.527
关键词: Lactate dehydrogenase 、 Pyruvate dehydrogenase lipoamide kinase isozyme 1 、 Biochemistry 、 Oxoglutarate dehydrogenase complex 、 Pyruvate dehydrogenase complex 、 Chemistry 、 Pyruvate decarboxylation 、 Pyruvate dehydrogenase phosphatase 、 Branched-chain alpha-keto acid dehydrogenase complex 、 Pyruvate dehydrogenase kinase
摘要: Pyruvate inhibition of lactate dehydrogenase activity crude human tissue extracts has been studied at both 25 ° and 37 °C. The tissues containing predominantly the slower moving isoenzymes is inhibited significantly less than that other tissues. These findings are not in accordance with some recently reported.
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