[12] Detection of polysialosyl-containing glycoproteins in brain using prokaryotic-derived probes
作者： Frederic A. Troy , Patrick C. Hallenbeck , Ronald D. McCoy , Eric R. Vimr
DOI: 10.1016/0076-6879(87)38014-0
关键词: Sialoglycoproteins 、 Glycoconjugate 、 Neural cell 、 Polysialic acid 、 Neural cell adhesion molecule 、 Biochemistry 、 Adhesion 、 Function (biology) 、 Biology 、 Glycoprotein
摘要: Publisher Summary Several laboratories have described a class of high molecular weight surface sialoglycoproteins that function in neural cell adhesion and brain development. This chapter discusses the probes recognize or synthesize polysialic acid containing α-2,8-ketosidic linkages. These been used combination with structural studies to prove presence polysialosyl carbohydrate units membranes embryonic chick rat brains; quantitate amount [ 14 C]NeuNAc incorporated specifically into α-2,8-1inked molecule (N-CAM) by CMP-NeuNAc:poly- α-2,8-sialosyl sialy ferase; show on N-CAM has direct effect mediated this is important for normal development nerve tissue. use these detect bacterial glycoconjugates. The also prokaryotic-derived polysialosyl-containing glycoprotein brain.
sci-hub.se 参考文章(38)
R D McCoy, E R Vimr, F A Troy, CMP-NeuNAc:poly-alpha-2,8-sialosyl sialyltransferase and the biosynthesis of polysialosyl units in neural cell adhesion molecules. Journal of Biological Chemistry. ,vol. 260, pp. 12695- 12699 ,(1985) , 10.1016/S0021-9258(17)38929-9
Roland Schauer, Chemistry, Metabolism, and Biological Functions of Sialic Acids Advances in Carbohydrate Chemistry and Biochemistry. ,vol. 40, pp. 131- 234 ,(1982) , 10.1016/S0065-2318(08)60109-2
J B Rothbard, R Brackenbury, B A Cunningham, G M Edelman, Differences in the carbohydrate structures of neural cell-adhesion molecules from adult and embryonic chicken brains. Journal of Biological Chemistry. ,vol. 257, pp. 11064- 11069 ,(1982) , 10.1016/S0021-9258(18)33933-4
C Whitfield, D A Adams, F A Troy, Biosynthesis and assembly of the polysialic acid capsule in Escherichia coli K1. Role of a low-density vesicle fraction in activation of the endogenous synthesis of sialyl polymers. Journal of Biological Chemistry. ,vol. 259, pp. 12769- 12775 ,(1984) , 10.1016/S0021-9258(18)90812-4
J Finne, Occurrence of unique polysialosyl carbohydrate units in glycoproteins of developing brain. Journal of Biological Chemistry. ,vol. 257, pp. 11966- 11970 ,(1982) , 10.1016/S0021-9258(18)33661-5
F A Troy, M A McCloskey, Role of a membranous sialyltransferase complex in the synthesis of surface polymers containing polysialic acid in Escherichia coli. Temperature-induced alteration in the assembly process. Journal of Biological Chemistry. ,vol. 254, pp. 7377- 7387 ,(1979) , 10.1016/S0021-9258(18)50329-X
R Roy, F Michon, H J Jennings, Determinant specificities of the groups B and C polysaccharides of Neisseria meningitidis. Journal of Immunology. ,vol. 134, pp. 2651- 2657 ,(1985)
E C Gotschlich, B A Fraser, O Nishimura, J B Robbins, T Y Liu, Lipid on capsular polysaccharides of gram-negative bacteria. Journal of Biological Chemistry. ,vol. 256, pp. 8915- 8921 ,(1981) , 10.1016/S0021-9258(19)52486-3
T.E. Rohr, F.A. Troy, Structure and biosynthesis of surface polymers containing polysialic acid in Escherichia coli. Journal of Biological Chemistry. ,vol. 255, pp. 2332- 2342 ,(1980) , 10.1016/S0021-9258(19)85895-7
B Kwiatkowski, B Boschek, H Thiele, S Stirm, Endo-N-acetylneuraminidase associated with bacteriophage particles. Journal of Virology. ,vol. 43, pp. 697- 704 ,(1982) , 10.1128/JVI.43.2.697-704.1982