Full genomic analysis of an influenza A (H1N2) virus identified during 2009 pandemic in Eastern India: evidence of reassortment event between co-circulating A(H1N1)pdm09 and A/Brisbane/10/2007-like H3N2 strains
作者： Tapasi Roy Mukherjee , Anurodh S Agrawal , Sekhar Chakrabarti , Mamta Chawla-Sarkar
关键词: Virus 、 Pandemic 、 Genome 、 Virology 、 Genetics 、 Gene 、 Biology 、 Reassortant Viruses 、 Human mortality from H5N1 、 Influenza A virus 、 Reassortment
摘要: During the pandemic [Influenza A(H1N1)pdm09] period in 2009-2010, an influenza A (Inf-A) virus with H1N2 subtype (designated as A/Eastern India/N-1289/2009) was detected from a 25 years old male Mizoram (North-eastern India). To characterize full genome of virus. For initial detection Influenza viruses, amplification matrix protein (M) gene Inf-A and B viruses carried out by real time RT-PCR. positive are then further subtyped HA NA specific primers. Sequencing phylogenetic analysis performed for strain to understand its origin. The outcome this study revealed unique reassortment event where N-1289 acquired it’s 2009 H1N1 swine origin other genes H3N2-like human This provides information on possibility occurrence events during season when infectivity is high two different subtypes co-circulate same geographical location.
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Amy L. Vincent, Wenjun Ma, Kelly M. Lager, Bruce H. Janke, Jürgen A. Richt, Chapter 3 Swine Influenza Viruses: A North American Perspective Advances in Virus Research. ,vol. 72, pp. 127- 154 ,(2008) , 10.1016/S0065-3527(08)00403-X
Munemura T, Kawakami C, Odagiri T, Takaoka M, Tashiro M, Noguchi Y, Nakajima S, Saikusa M, Ito R, Saito T, Fujii K, Nakaya Y, Isolation of influenza A H1N2 viruses from an outbreak in Yokohama City during the 2001-2002 influenza season in Japan. Japanese Journal of Infectious Diseases. ,vol. 56, pp. 110- 113 ,(2003)
J.A.L. Ives, J.A. Carr, D.B. Mendel, C.Y. Tai, R. Lambkin, L. Kelly, J.S. Oxford, F.G. Hayden, N.A. Roberts, The H274Y mutation in the influenza A/H1N1 neuraminidase active site following oseltamivir phosphate treatment leave virus severely compromised both in vitro and in vivo. Antiviral Research. ,vol. 55, pp. 307- 317 ,(2002) , 10.1016/S0166-3542(02)00053-0
Wallace D Bulimo, Jason L Garner, David C Schnabel, Sheryl A Bedno, M Kariuki Njenga, Walter O Ochieng, Evans Amukoye, James M Magana, James M Simwa, Victor O Ofula, Samwel M Lifumo, Julia Wangui, Robert F Breiman, Samuel K Martin, None, Genetic analysis of H3N2 influenza A viruses isolated in 2006–2007 in Nairobi, Kenya Influenza and Other Respiratory Viruses. ,vol. 2, pp. 107- 113 ,(2008) , 10.1111/J.1750-2659.2008.00044.X
Xiyan Xu, Catherine B. Smith, Bruce A. Mungall, Stephen E. Lindstrom, Henrietta E. Hall, Kanta Subbarao, Nancy J. Cox, Alexander Klimov, Intercontinental Circulation of Human Influenza A(H1N2) Reassortant Viruses during the 2001–2002 Influenza Season The Journal of Infectious Diseases. ,vol. 186, pp. 1490- 1493 ,(2002) , 10.1086/344738
E. Hoffmann, J. Stech, Y. Guan, R. G. Webster, D. R. Perez, Universal primer set for the full-length amplification of all influenza A viruses. Archives of Virology. ,vol. 146, pp. 2275- 2289 ,(2001) , 10.1007/S007050170002
Amy L. Vincent, Wenjun Ma, Kelly M. Lager, Marie R. Gramer, Juergen A. Richt, Bruce H. Janke, Characterization of a newly emerged genetic cluster of H1N1 and H1N2 swine influenza virus in the United States Virus Genes. ,vol. 39, pp. 176- 185 ,(2009) , 10.1007/S11262-009-0386-6
Tapasi Roy, Anurodh S. Agrawal, Anupam Mukherjee, Akhilesh C. Mishra, Mandeep S. Chadha, Harpreet Kaur, Mamta Chawla-Sarkar, Surveillance and molecular characterization of human influenza B viruses during 2006–2010 revealed co-circulation of Yamagata-like and Victoria-like strains in eastern India Infection, Genetics and Evolution. ,vol. 11, pp. 1595- 1601 ,(2011) , 10.1016/J.MEEGID.2011.05.022
Yun Hee Baek, Jeung Hyun Park, Young Jun Song, Min-Suk Song, Philippe Noriel Q. Pascua, Yoon-Soo Hahn, Heon-Seok Han, Ok-Jun Lee, Ki-Soon Kim, Chun Kang, Young-Ki Choi, Molecular characterization and phylogenetic analysis of H3N2 human influenza A viruses in Cheongju, South Korea The Journal of Microbiology. ,vol. 47, pp. 91- 100 ,(2009) , 10.1007/S12275-008-0207-Y
Mehuli Sarkar, Anurodh S. Agrawal, Rakhi Sharma Dey, Shiladitya Chattopadhyay, Ranajoy Mullick, Papiya De, Sekhar Chakrabarti, Mamta Chawla-Sarkar, Molecular characterization and comparative analysis of pandemic H1N1/2009 strains with co-circulating seasonal H1N1/2009 strains from eastern India Archives of Virology. ,vol. 156, pp. 207- 217 ,(2011) , 10.1007/S00705-010-0842-6