Macrophage metabolism in atherosclerosis

作者: Gael F. P. Bories , Norbert Leitinger

DOI: 10.1002/1873-3468.12786

关键词: InflammationMetabolismProinflammatory cytokineLipid accumulationCancer researchImmunologyMacrophageContext (language use)ApoptosisLipoproteinBiology

摘要: … feeds the TCA cycle and sustains M2 macrophage polarization upon IL-4 … Activation of macrophages by LPS promotes PKM2 … was once considered a cholesterol deposition disease, but …

参考文章(180)
Padmapriya Rao, Srigiridhar Kotamraju, Sathish Babu Vasamsetti, High Glucose Induced Monocyte-to-Macrophage Differentiation: Role of AMPk The FASEB Journal. ,vol. 27, ,(2013)
Eduardo J. Folco, Yuri Sheikine, Viviane Z. Rocha, Thomas Christen, Eugenia Shvartz, Galina K. Sukhova, Marcelo F. Di Carli, Peter Libby, Hypoxia But Not Inflammation Augments Glucose Uptake in Human Macrophages: Implications for Imaging Atherosclerosis With 18Fluorine-Labeled 2-Deoxy-D-Glucose Positron Emission Tomography Journal of the American College of Cardiology. ,vol. 58, pp. 603- 614 ,(2011) , 10.1016/J.JACC.2011.03.044
Cong Li, Xiao Yan Ding, Dong Mei Xiang, Jie Xu, Xiang Lan Huang, Fan Fan Hou, Qiu Gen Zhou, Enhanced M1 and Impaired M2 Macrophage Polarization and Reduced Mitochondrial Biogenesis via Inhibition of AMP Kinase in Chronic Kidney Disease. Cellular Physiology and Biochemistry. ,vol. 36, pp. 358- 372 ,(2015) , 10.1159/000430106
R.B. Lorsbach, W.J. Murphy, C.J. Lowenstein, S.H. Snyder, S.W. Russell, Expression of the nitric oxide synthase gene in mouse macrophages activated for tumor cell killing. Molecular basis for the synergy between interferon-gamma and lipopolysaccharide. Journal of Biological Chemistry. ,vol. 268, pp. 1908- 1913 ,(1993) , 10.1016/S0021-9258(18)53940-5
Yi Qun Xiao, Celio G. Freire-de-Lima, William P. Schiemann, Donna L. Bratton, R. William Vandivier, Peter M. Henson, Transcriptional and Translational Regulation of TGF-β Production in Response to Apoptotic Cells Journal of Immunology. ,vol. 181, pp. 3575- 3585 ,(2008) , 10.4049/JIMMUNOL.181.5.3575
Intensive blood glucose control and vascular outcomes in patients with type 2 diabetes. The New England Journal of Medicine. ,vol. 358, pp. 2560- 2572 ,(2008) , 10.1056/NEJMOA0802987
M.W.J. Cleeter, J.M. Cooper, V.M. Darley-Usmar, S. Moncada, A.H.V. Schapira, Reversible inhibition of cytochrome c oxidase, the terminal enzyme of the mitochondrial respiratory chain, by nitric oxide FEBS Letters. ,vol. 345, pp. 50- 54 ,(1994) , 10.1016/0014-5793(94)00424-2
Juan-Carlos Rodríguez-Prados, Paqui G. Través, Jimena Cuenca, Daniel Rico, Julián Aragonés, Paloma Martín-Sanz, Marta Cascante, Lisardo Boscá, Substrate Fate in Activated Macrophages: A Comparison between Innate, Classic, and Alternative Activation Journal of Immunology. ,vol. 185, pp. 605- 614 ,(2010) , 10.4049/JIMMUNOL.0901698
Wen Qiang Chen, Lin Zhong, Lei Zhang, Xiao Ping Ji, Mei Zhang, Yu Xia Zhao, Cheng Zhang, Yun Zhang, Oral rapamycin attenuates inflammation and enhances stability of atherosclerotic plaques in rabbits independent of serum lipid levels British Journal of Pharmacology. ,vol. 156, pp. 941- 951 ,(2009) , 10.1111/J.1476-5381.2008.00102.X
Anthony J. Covarrubias, H. Ibrahim Aksoylar, Tiffany Horng, Control of macrophage metabolism and activation by mTOR and Akt signaling Seminars in Immunology. ,vol. 27, pp. 286- 296 ,(2015) , 10.1016/J.SMIM.2015.08.001