作者: Jennifer Wu
DOI:
关键词: Antibody 、 Virology 、 Biology 、 Monoclonal antibody 、 Major histocompatibility complex 、 Cancer
摘要: Disclosed are compositions and methods relating to antibodies that bind soluble Major Histocompatibility Complex class I chain-related (sMIC). Specifically, disclosed designed or selected inhibit sMIC (e.g. neutralize sMIC) shed from MIC+ tumors. Further of using the for treatment MlC-positive cancers.