Protein analysis based on molecular beacon probes and biofunctionalized nanoparticles
作者： Hui Shi , XiaoXiao He , XiaoHai Yang , KeMin Wang , Qing Wang
DOI: 10.1007/S11426-010-0110-3
关键词: Aptamer 、 Dna interaction 、 Protein–DNA interaction 、 Surface protein 、 Nanotechnology 、 Chemistry 、 Proteomics 、 Molecular beacon 、 Binding process 、 Nanoparticle 、 General chemistry
摘要: With the completion of human genome-sequencing project, there has been a resulting change in focus studies from genomics to proteomics. By utilizing inherent advantages molecular beacon probes and biofunctionalized nanoparticles, series novel principles, methods techniques have exploited for bioanalytical biomedical studies. This review mainly discusses applications nanoparticles-based technologies real-time, in-situ, highly sensitive selective protein analysis, including nonspecific or specific detection separation, protein/DNA interaction studies, cell surface recognition, antigen-antibody binding process-based bacteria assays. The introduction nanoparticles into analysis area would necessarily advance proteomics research.
springer.com
sci-hub.se 参考文章(143)
Xia Lin, Kemin Wang, Xiaoxiao He, Weihong Tan, Jiyun Chen, Yin Yuan, Jinghua Duan, Study on the effect of electrostatic interaction on core-shell nanoparticles preparation with microemulsion technique Chinese Science Bulletin. ,vol. 50, pp. 2821- 2826 ,(2005) , 10.1360/982005-689
Sanjay Tyagi, Salvatore A.E. Marras, Fred Russell Kramer, Wavelength-shifting molecular beacons Nature Biotechnology. ,vol. 18, pp. 1191- 1196 ,(2000) , 10.1038/81192
XiaoXiao He, Rong Jin, Liu Yang, KeMin Wang, Wei Li, WeiHong Tan, HuiMin Li, Study on the specific interaction between angiogenin and aptamer by atomic force microscopy (AFM) Chinese Science Bulletin. ,vol. 53, pp. 198- 203 ,(2008) , 10.1007/S11434-007-0494-4
Stanley Fields, Proteomics in Genomeland Science. ,vol. 291, pp. 1221- 1224 ,(2001) , 10.1126/SCIENCE.291.5507.1221
Alison Abbott, A post-genomic challenge: learning to read patterns of protein synthesis Nature. ,vol. 402, pp. 715- 716 ,(1999) , 10.1038/45350
Ping Gong, Huimin Li, Xiaoxiao He, Kemin Wang, Jianbing Hu, Weihong Tan, Shouchun Zhang, Xiaohai Yang, Preparation and antibacterial activity of Fe3O4@Ag nanoparticles Nanotechnology. ,vol. 18, pp. 285604- ,(2007) , 10.1088/0957-4484/18/28/285604
Swadeshmukul Santra, Peng Zhang, Kemin Wang, Rovelyn Tapec, Weihong Tan, Conjugation of biomolecules with luminophore-doped silica nanoparticles for photostable biomarkers. Analytical Chemistry. ,vol. 73, pp. 4988- 4993 ,(2001) , 10.1021/AC010406+
Zhiwen Tang, Kemin Wang, Weihong Tan, Jun Li, Lingfeng Liu, Qiuping Guo, Xiangxian Meng, Shasheng Huang, Du Li, Weifang Luo, None, Real time monitoring of nucleic acids ligation based on molecular beacon Chinese Science Bulletin. ,vol. 48, pp. 1215- 1218 ,(2003) , 10.1007/BF03183940
XiaoHai Yang, Lei Wang, KeMin Wang, WeiHong Tan, HongXing Tang, XiangXian Meng, QiuPing Guo, Novel protein detection method based on proximity-dependent polymerase reaction and aptamers Chinese Science Bulletin. ,vol. 53, pp. 204- 208 ,(2008) , 10.1007/S11434-007-0487-3
Wei Li, Kemin Wang, Weihong Tan, Changbei Ma, Xiaohai Yang, Aptamer-based analysis of angiogenin by fluorescence anisotropy Analyst. ,vol. 132, pp. 107- 113 ,(2007) , 10.1039/B614138B