Alginate derivatization: a review of chemistry, properties and applications.
作者： Siddhesh N. Pawar , Kevin J. Edgar
DOI: 10.1016/J.BIOMATERIALS.2012.01.007
关键词: Monosaccharide 、 Derivatization 、 Organic chemistry 、 Biomolecule 、 Drug delivery 、 Chemistry 、 Self-healing hydrogels 、 Polysaccharide 、 Nucleic acid 、 Sequence (biology)
摘要: Alginates have become an extremely important family of polysaccharides because of their utility in preparing hydrogels at mild pH and temperature conditions, suitable for sensitive biomolecules like proteins and nucleic acids, and even for living cells such as islets of Langerhans. In addition, the complex monosaccharide sequences of alginates, and our growing ability to create controlled sequences by the action of isolated epimerases upon the alginate precursor poly (mannuronic acid), create remarkable opportunities for …
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